Active Clinical Trials and Research Studies


We are seeking healthy volunteers and individuals with Mild Cognitive Impairment (MCI) or Mild Alzheimer's Disease (AD) who are interested in taking part in a clinical research study to find out if functional MRI images of the brain can be used to diagnose and monitor the course and treatment of MCI and AD. Subjects must have a study partner and be willing to come to six to eight clinic visits over the course of two to three years.




Our Research. Your Story.

Research is happening at Massachusetts General Hospital (MGH) that is focused on learning about the cognitive abilities, personality, and other traits of people who have more than one blood relative affected with Frontotemporal Degeneration (FTD), Alzheimer’s disease, and related disorders.


You Can Contribute to the Cause


This study examines the effect of cognitive enhancement programs on age related changes in memory and attention.


We are seeking healthy, right-handed adults between the ages of 65-80. If eligible, you will receive 8 professional cognitive training sessions free of charge. You will also receive take-home exercises to supplement your training classes, and will be asked to complete these exercises daily for the duration of the 8-week program.



We are seeking healthy adults, aged 18 or older, to participate in a research study. The goal of the study is to examine olfactory function (or the sense of smell) in healthy individuals and in preclinical and clinical subjects with Alzheimer's Disease, Dementia with Lewy Bodies, or Frontotemporal Dementias.



What is our study about?

We want to see if there are brainwave abnormalities in the brains of people with Alzheimer’s Disease and determine whether there is a distinct brainwave signature for Alzheimer’s Disease. This is a study where you will wear a portable EEG, play memory games on an iPad, and then wear the device home for 3 days!


Are you eligible to participate?


Coming soon!


We are recruiting patients for the ENGAGE Study, which is evaluating the safety and efficacy of aducanumab (BIIB037) in slowing cognitive and functional impairment in patients with early Alzheimer’s disease.



 We are seeking healthy adults, 50 to 65, or 80 to 90 years of age to participate in a research study. The purpose of the study is to develop ways for understanding brain changes affecting memory and thinking that occur with age.



We will use PET and MRI imaging to study two different proteins in the brain, called amyloid and tau, to study their role in several brain disorders, including Alzheimer’s Disease and mild cognitive impairment. The study will take up to 1 month to complete and may take up to 5 visits. 


- Screening visit (including blood draw and other tests for eligibility)

- Cognitive testing


- Amyloid PET

- Tau PET (including arterial blood sampling)


Study Population: Healthy volunteers, AD and MCI patients (ages 55-85)

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