Active Clinical Trials and Research Studies

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What is the purpose of this research study?

The purpose of this clinical trial is to evaluate the efficacy, safety and tolerability of BAN2401, a drug that may have the potential to treat Alzheimer's disease (AD). In AD, there are abnormally-high levels of a protein, called amyloid beta, in the brain. We hope that BAN2401 can reduce the amount of amyloid.

 

Who is eligible?

We are looking for participants who:

-- have been diagnosed with Mild Cognitive Impairment (MCI) or mild Alzheimer's disease dementia

-- are between the age of 50 and 90

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The purpose of this clinical trial is to evaluate the safety of PF-05212377 (SAM-760) and the effect of PF-05212377 (SAM-760) on cognition and some behavioral symptoms associated with Alzheimer's disease.

 

We are looking for participants who:

 

-- have a diagnosis of Alzheimer's disease

-- are age 60 or older

-- have a reliable caregiver or family member who is able to accompany them to study visits

-- are in stable medical condition

-- are on stable doses of Aricept (donepezil)

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The purpose of this clinical trial is to evaluate the efficacy, safety and tolerability of solaneuzumab, a drug that may have the potential to slow the onset of Alzheimer's disease (AD). In AD, there are abnormally high levels of a protein, called amyloid in the brain. We hope that solaneuzumab can reduce the amount of amyloid in the brain.

 

We are looking for participants who:

-- do not have memory problem

-- are between age 65 and 85

-- have a reliable caregiver or family member who knows them well

-- are in stable medical condition

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Researchers from the Massachusetts General Hospital (MGH) ducting a research study to study the way brains change with age.   

 

You may be eligible to participate if you:

-- are age 20 to 90 and speak English

 

This research study involves:

-- up to 6 visits to the MGH over 6 months

-- evaluations, including memory tests and brain scans

 

You will receive:

-- up to $700 for participating in the total study ($50 - $200 paid per visit)

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What is DIAN?

DIAN stands for the Dominantly Inherited Alzheimer’s Network.  This international network has been established by the National Institute on Aging of the National Institutes of Health (US) to bring together researchers who study genetic forms of Alzheimer’s disease (AD). 

 

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The purpose of this study is to find out if a new drug called Solanezumab can help people with Alzheimer's disease (AD). We also want to find out if Solanezumab is safe to take without causing too many side effects. In AD, amyloid fragments gather and form hard plaques. Doctors think that amyloid can cause symptoms such as memory loss and confusion. We hope that Solanezumab can reduce the amount of amyloid in the brain.

 

Who is eligible?

Please see attached.

Active

We are seeking healthy volunteers and individuals with Mild Cognitive Impairment (MCI) or Mild Alzheimer's Disease (AD) who are interested in taking part in a clinical research study to find out if functional MRI images of the brain can be used to diagnose and monitor the course and treatment of MCI and AD. Subjects must have a study partner and be willing to come to six to eight clinic visits over the course of two to three years.

 

Active

We are seeking healthy adults, 60 to 90 years of age to participate in a research study. The purpose of the study is to develop ways for understanding memory changes that occur with age. Participants will be asked questions about their memory and must have a friend or relative who can answer ten minutes of questions over the telephone about day-to-day activities.

 

Active

The purpose of this study is to find out if a type of insulin (Humulin® R) improves memory when it is given intranasally (as a "nasal spray") to adults with a mild cognitive (memory) impairment or early Alzheimer's disease (AD). This study will also look at the effect of intranasal insulin (INI) has on the brain structure and function and markers of AD in the cerebrospinal fluid (CSF) and blood.

 

More information is attached.

 

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