Publications by Center Staff

Current Options for Managing Alzheimer's Disease: Treating Symptoms and Slowing Disease Progression
1999

Pendlebury WW and Solomon PR (1999). Current options for managing alzheimer's disease: treating symptoms and slowing disease progression. Women's Health in Primary Care; 2: 880-888.

Demonstration by Fluorescence Resonance Energy Transfer of a Close Association between Activated MAP Kinase and Neurofibrillary Tangles: Implications for MAP Kinase Activation in Alzheimer Disease
1999

Knowles RB, Chin J, Ruff CT and Hyman BT (1999). Demonstration by fluorescence resonance energy transfer of a close association between activated map kinase and neurofibrillary tangles:  implications for map kinase activation in alzheimer disease. J Neuropath Exp Neurology: 58: 1090-1098.

DNA Strand Breaks in Alzheimer’s Disease
1999

Adamec E, Vonsattel JP and Nixon RA (1999). dna strand breaks in alzheimer’s disease. Brain Res; 849: 67-77.

Effects of the Amyloid Precursor rotein Glu693 ----> Gln 'Dutch' Mutation on the Production and Stability of Amyloid Beta-Protein
1999

Watson DJ, Selkoe DJ and Teplow DB (1999). Effects of the amyloid precursor protein glu693 ---> gln 'dutch' mutation on the production and stability of amyloid beta-protein. Biochem J; 340: 703-709.

Lack of Allelic Imbalance in APOE E-3/4 Brain mRNA Expression in Alzheimer's Disease
1999

Growdon JH, Cheung BS, Hyman BT and Rebeck GW (1999). Lack of allelic imbalance in apoe d-3/4 brain mrna expression in alzheimer's disease. Neuroscience Letters; 272: 83-86.

Lack of Independent Associations of Apolipoprotein E Promoter and Intro 1 Polymorphisms with Alzheimer's Disease
1999

Rebeck GW, Cheung BS, Growdon WB, Deng A, Akuthota P, Locascio J, Greenberg SM and Hyman BT (1999). Lack of independent associations of apolipoprotein e promoter and intro 1 polymorphisms with alzheimer's disease. Neurosci Letters; 272: 155-158.

Neural Mechanisms of Delirium: Current Hypotheses and Evolving Concepts
1999

Flacker JM and Lipsitz LA (1999). Neural mechanisms of delirium: current hypotheses and evolving concepts. J Geron: Biol Sci; 54A: B239-B246.

Peptidomimetic Probes and Molecular Modeling Suggest that Alzheimer's Gamma-Secretase is an Intramembrane-Cleaving Aspartyl Protease
1999

Wolfe MS, Xia W, Moore CL, Leatherwood DD, Ostaszewski B, Rahmati T, Donkor I and Selkoe DJ (1999).  Peptidomimetic probes and molecular modeling suggest that alzheimer's gamma-secretase is an intramembrane-cleaving aspartyl protease. Biochem; 38: 4720-4727.

Receptor-Mediated Transport of Human Amyloid Beta-Protein 1-40 and 1-42 at the Blood-Brain Barrier
1999

Poduslo JF, Curran GL, Sanyal B and Selkoe DJ (1999). Receptor-mediated transport of human amyloid beta-protein 1-40 and 1-42 at the blood-brain barrier. Neurobiol of Disease; 6: 190-199.

Review: Translating Cell Biology into Therapeutic Advances in Alzheimer's Disease
1999

Selkoe DJ (1999). Review: translating cell biology into therapeutic advances in alzheimer's disease. Nature; 39(Supp): A23-A31.