Publications by Center Staff

Presenilin-Mediated Modulation of Capacitative Calcium Entry
2000

Yoo, AS, Cheng I, Chung S, Grenfell TZ, Lee H, Pack-Chung E, Handler M, Shen J, Xia W, Tesco G, Saunders AJ, Ding K, Frosch MP, Tanzi RE and Kim TW (2000). Presenilin-mediated modulation of capacitative calcium entry. Neuron; 27: 561-572.

Protofibrillar Intermediates of Amyloid Beta-Protein Induce Acute Electrophysiological Changes and Progressive Neurotoxicity in Cortical Neurons
2000

Hartley DM, Walsh DM, Ye CP, Diehl T, Vasquez S, Vassilev PM, Teplow DB and Selkoe DJ (2000). Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J Neurosci; 19: 8876-8884.

Purified Recombinant Insulin-Degrading Enzyme Degrades Amyloid Beta-Protein but does not Promote its Oligomerization
2000

Chesneau V, Vekrellis K, Rosner MR and Selkoe DJ (2000). Purified recombinant insulin-degrading enzyme degrades amyloid beta-protein but does not promote its oligomerization. Biochem J; 351: 509-516.

Statins and the Risk of Dementia
2000

Jick H, Zornberg GL, Jick SS, Seshadri S and Drachman DA (2000). Statins and the risk of dementia. Lancet; 356: 1627-1631.

The Cost of Recruiting Alzheimer’s Disease Caregivers for Research
2000

Tarlow B and Mahoney D (2000). The cost of recruiting alzheimer’s disease caregivers for research. J Aging and Health; 11: 519-539.

The Oligomerization of Amyloid Beta-Protein Begins Intracellularly in Cells Derived from Human Brain
2000

Walsh DM, Tseng BP, Rydel RD, Podlinsy MB and Selkoe DJ (2000). The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain. Biochem; 39: 10831-10839.

The Selective Muscarinic M1 Agonist AF102B Decreases Levels of Total ABeta in Cerebrospinal Fluid of Patients with Alzheimer’s Disease
2000

Nitsch RM, Deng M, Tennis M, Schoenfeld D and Growdon JH (2000).  The selective muscarinic m1 agonist af102b decreases levels of total abeta in cerebrospinal fluid of patients with alzheimer’s disease. Ann Neurol; 48: 913-918.
 

Up-Regulation of the Lysosomal System in Experimental Models of Neuronal Injury: Implications for Alzheimer's Disease
2000

Adamec E, Mohan PS, Cataldo AM, Vonsattel JP and Nixon RA (2000). Up-regulation of the lysosomal system in experimental models of neuronal injury: implications for alzheimer's disease. Neuroscience; 100: 663-675.

A2A Adenosine Receptor Deficiency Attenuates Brain Injury Induced by Transient Focal Ischemia in Mice
1999

Chen JF, Huang Z, Ma J, Zhu J, Moratallo R, Standaert D, Moskowitz MA, Fink JS and Schwarzschild MA (1999). A2A adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice. J Neurosci; 19: 9192-9200.

Amyloid beta-Protein Fibrillogenesis
1999

Walsh DM, Hartley DM, Kusumoto Y, Fezoui Y, Condron MM, Lomakin A, Benedek GB, Selkoe DJ and Teplow DB (1999). Amyloid beta-protein fibrillogenesis. J Biol Chem; 274: 25945-25952.