Peptidomimetic Probes and Molecular Modeling Suggest that Alzheimer's Gamma-Secretase is an Intramembrane-Cleaving Aspartyl Protease

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Wolfe MS, Xia W, Moore CL, Leatherwood DD, Ostaszewski B, Rahmati T, Donkor I and Selkoe DJ (1999).  Peptidomimetic probes and molecular modeling suggest that alzheimer's gamma-secretase is an intramembrane-cleaving aspartyl protease. Biochem; 38: 4720-4727.