- Education, Training & Outreach
- Patients & Caregivers
- For Investigators
- News on Dementia
- Media Room
- Donate & Contact
Peptidomimetic Probes and Molecular Modeling Suggest that Alzheimer's Gamma-Secretase is an Intramembrane-Cleaving Aspartyl Protease
Wolfe MS, Xia W, Moore CL, Leatherwood DD, Ostaszewski B, Rahmati T, Donkor I and Selkoe DJ (1999). Peptidomimetic probes and molecular modeling suggest that alzheimer's gamma-secretase is an intramembrane-cleaving aspartyl protease. Biochem; 38: 4720-4727.