Pathway Analysis of Parkinson’s Reveals PGC-1a as Therapeutic Target for Early Intervention

Publication Date: 
2010

Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, Eklund AC, Zhang-James Y, Kim PD, Hauser MA, Grünblatt E, Moran LB, Mandel SA, Riederer P, Miller RM, Federoff HJ, Wüllner U, Papapetropoulos S, Youdim MB, Cantuti-Castelvetri I, Young AB, Vance JM, Davis RL, Hedreen JC, Adler CH, Beach TG, Graeber MB, Middleton FA, Rochet J-C, Scherzer CR and the Global PD Gene Expression (GPEX) Consortium Center (2010).  Pathway analysis of Parkinson’s reveals PGC-1a as therapeutic target for early intervention.  Sci Transl Med; 2:  52ra7; doi:  10.1126/scitranslmed.3001059. NIHMSID - In Process.