Longitudinal Cohort ('LC') Study

The ‘LC’ study is an ongoing observational study of a group of individuals with or without memory problems. Also known as a natural history study, the goal of the long-term study is to obtain a uniform set of data from individuals who have various types of dementia (e.g., Alzheimer’s disease, frontotemporal degeneration, lewy body dementia, etc..) and from healthy older individuals in order to understand how dementia (a decline in mental ability) develops in the human brain. Research findings from the ‘LC’ study will enable scientists to find effective treatments and an eventual cure for Alzheimer’s disease and related forms of neurological diseases.

What is involved?

  • An annual physical & neurologic exam
  • An annual (‘paper & pencil’ or computerized) set of neuropsychological tests to test memory & related functions
  • Willingness to provide small amounts of biomarker (e.g., blood, saliva, etc..) samples
  • Willingness to participate in brain imaging tests
  • Interest in hearing more about brain donation for research
  • Individuals must have a reliable study partner to participate in the study

Interested to find out more about the study? Call us at 617-643-5200 for more information!