This is a Phase 3, safety and efficacy study of Dimebon for the treatment of Alzheimer's disease. Study participants are asked to come for study-related visits 10 times during a 1-year period, take study medications as directed by study personnel, and complete all study-related procedures.
1. Have mild to moderate Alzheimer's disease.
2. Be 50 years of age or older.
3. Have been taking Aricept (Donepezil) for at least 6 months.
4. Have a caregiver who assists (or directly supervises) the participant at least 5 days per week for at least 3 hours a day.
5. Living in the community and may be living in an assisted-care facility if living independently.
More information about the study may be found on the attached document.
We are now enrolling men and women, ages 45 to 90, with memory loss or mild cognitive impairment (MCI) to participate in this study. A study partner will also be needed to participate in this study. Volunteers may receive investigational medication, study-related medical care, laboratory testing and cognitive testing.
John H. Growdon, MD, of the Department of Neurology at the Massachusetts General Hospital is conducting an outpatient research study on brothers and/or sisters who developed Alzheimer's disease on or after age sixty for a National Cell Repository for Alzheimer's disease. To be eligible, a family must have two living brothers and/or sisters who developed Alzheimer's disease on or after age sixty.
The goal of the study is to find new genes that may play a role in the development of late-onset Alzheimer's disease and to understand how they work. There is no stipend, but any costs will be reimbursed.
We are seeking healthy volunteers and patients with MIild Cognitive Impairment or Mild Alzheimer's disease, ages fifty to ninety, who are interested in taking part in a clinical research study to look at the usefulness of brain scans, cognitive tests and biomarkers to identify early stages of Alzheimer's disease.
Subjects must have a study partner and be willing to come to six to eight visits over the course of two to three years. At each of these visits, subjects will be asked to have blood drawn, undergo tests of memory and have an MRI scan of the brain. All information is kept completely confidential.
We are seeking adults, sixty-five years of age or order, with at least four years of education, from a variety of ethnic backgrounds to participate in a research study. The purpose of the study is to develop simple methods for understanding memory changes with age.
Participants will be asked questions about their memory and must have a friend or relative who can answer five minutes of questions over the telephone about day-to-day activities. All evaluations will be free of cost and reimbursement for time and transportation is provided. All information is kept confidential.
1. Sixty-five years of age or older.
2. Speak English.
3. Have a friend or relative who can answer five minutes of questions over the telephone about day-to-day activities.