Annual Pilot

The Role of Autophagic Protein Turnover in the Production of Amyloid Beta Proteins in Neurons

Project Year(s): 
1994 - 1995
Principal Investigator(s): 

Peter J. Hollenbeck, PhD

Most Recent/Current Position(s): 

Associate Head & Professor (Biological Sciences), Purdue University

Neurophysiology Analysis of a Computational Model of Alzheimer's Disease

Project Year(s): 
1994 - 1995
Principal Investigator(s): 

Michael E. Hasselmo, PhD

Most Recent/Current Position(s): 

Professor (Psychology), Boston University

Effects of Total Cholinergic Denervation on Beta APP Expression and Toxicity

Project Year(s): 
1994 - 1995
Principal Investigator(s): 

Changiz Geula, PhD

Most Recent/Current Position(s): 

Director, Laboratory for Molecular/Cognitive Morphometry & Neuropathology Core Investigator, Northwestern ADC & Research Professor (Neuroscience), Northwestern University

Molecular Characterization of APP-Like Gene Family

Project Year(s): 
1993 - 1994
Principal Investigator(s): 

Wilma M. Wasco, PhD

Most Recent/Current Position(s): 

Associate Professor (Neurology), Harvard Medical School

AD-Like Changes in Alzheimer's Disease Neuronal Channels

Project Year(s): 
1993 - 1994
Principal Investigator(s): 

Walter J. Koroshetz, MD

Most Recent/Current Position(s): 

Deputy Director, NIH/NINDS & Professor (Neurology), Harvard Medical School

A Short Amyloid Peptide Inhibits Neuronal Calcium Channels

Project Year(s): 
1993 - 1994
Principal Investigator(s): 

Vernon M. Ingram, PhD

Most Recent/Current Position(s): 

(Former) John and Dorothy Wilson Professor (Biochemistry), Massachusetts Institute of Technology

Mitochondrial Energy Metabolism and Oxidative DNA Damage in Lymphoblastoid Cells from Patients with Familial Alzheimer's Disease

Project Year(s): 
1993 - 1994
Principal Investigator(s): 

Allen C. Bowling, MD, PhD

Most Recent/Current Position(s): 

Neurologist, Rocky Mountain Multiple Sclerosis Center, Englewood, CO

The Neurotoxicity of Beta Amyloid Protein in a Primate Brain

Project Year(s): 
1992 - 1993
Principal Investigator(s): 

Bruce A. Yankner, MD

Most Recent/Current Position(s): 

Professor (Pathology & Neurology), Harvard Medical School

Conditions Promoting Survival and Hypertrophy of Cortical Neurons Expressing Calbindin and Paravalbumin

Project Year(s): 
1992 - 1993
Principal Investigator(s): 

Ann M. Graybiel, PhD

Most Recent/Current Position(s): 

Walter A. Rosenblith Professor (Neuroscience), Massachusetts Institute of Technology

Investigation of the Prion Protein's Role as a Neuro-Trophic Factor

Project Year(s): 
1992 - 1993
Principal Investigator(s): 

Gerald D. Fischbach, MD

Most Recent/Current Position(s): 

Scientific Director, The Simons Foundation & (Former) Director, NIH/NINDS & (Former) Dean, Faculty of Health Sciences & Faculty of Medicine, Columbia University

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