Annual Pilot

Generation of a Possible Alzheimer's Disease Model by mating Calcineurin-Deficient Mice with Transgenic Mice Expressing Human Tau

Project Year(s): 
1997 - 1998
Principal Investigator(s): 

Usamah S. Kayyali, PhD, MPH

Most Recent/Current Position(s): 

Assistant Professor (Medicine), Tufts University

A New Regulatory Pathway for the Control of Brain Energy Metabolism

Project Year(s): 
1996 - 1997
Principal Investigator(s): 

James A. Nathanson, MD, PhD

Most Recent/Current Position(s): 

Unknown

Amyloid Beta Peptide Modulation of Cytokine and Neurotrophic Factor Gene Expression in CNS

Project Year(s): 
1996 - 1997
Principal Investigator(s): 

Linda Kobierski, PhD

Most Recent/Current Position(s): 

Unknown

The Relationship Between Beta Amyloid and Deposition and Neuritic Density

Project Year(s): 
1996 - 1997
Principal Investigator(s): 

Adriana B. Ferreira, MD, PhD

Most Recent/Current Position(s): 

Investigator, Neuropathology Core, Northwestern ADC & Associate Professor (Cell & Molecular Biology), Northwestern University

Role of S182 in BAPP Production

Project Year(s): 
1996 - 1997
Principal Investigator(s): 

Sherry Bursztain, PhD

Most Recent/Current Position(s): 

Research Associate Professor (Pathology), Dartmouth Hitchcock Medical Center

Potential Contribution of Recapitulation of Astroglial Secretion of Amyloid Precursor Protein to the Neuropathology of Alzheimer's Disease

Project Year(s): 
1995 - 1996
Principal Investigator(s): 

Thomas B. Shea, PhD

Most Recent/Current Position(s): 

Director, Center for Cellular Neurobiology and Neurodegeneration Research & Professor (Biological Sciences & Biochemistry), University of Massachusetts, Lowell

Neuronal Counts in Alzheimer's Disease Brain by the Stereological Method

Project Year(s): 
1995 - 1996
Principal Investigator(s): 

Teresa Gomez-Isla, MD, PhD

Most Recent/Current Position(s): 

Associate Professor (Neurology), Harvard Medical School

In Vitro Effects of Excessive Phosphorylation of Cytoskeletal Integrity of and Cell Wall Viability: A Potential Model of Neurodegeneration in Alzheimer's Disease

Project Year(s): 
1995 - 1996
Principal Investigator(s): 

Ann C. McKee, MD

Most Recent/Current Position(s): 

Director, Neuropathology Core, Boston University ADC & Associate Professor (Neurology and Pathology), Boston University

Studies of a Novel Biochemical Marker of Altered Cortical Activity in Alzheimer's Disease

Project Year(s): 
1995 - 1996
Principal Investigator(s): 

Andrew J. Cole, MD

Most Recent/Current Position(s): 

Director, Epilepsy Service, Massachusetts General Hospital & Associate Professor (Neurology), Harvard Medical School

Familial Alzheimer's Disease: Do Different Mutations Cause the Same Disease?

Project Year(s): 
1994 - 1995
Principal Investigator(s): 

Carol F. Lippa, MD

Most Recent/Current Position(s): 

Director, Memory Disorders Program, Dementia Research Laboratory, Neurology Brain, Blood and CSF Bank & Professor (Neurology), Drexel University

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