Annual Pilot

Investigating Metal-Mediated Redox Properties of Endogenous Human A-Beta and Oxidatively Amyloidgenic Processing APP in Alzheimer's Disease

Project Year(s): 
2000 - 2001
Principal Investigator(s): 

Xudong Huang, PhD

Most Recent/Current Position(s): 

Assistant Professor (Radiology), Harvard Medical School

The Alteration of the Beta-Amyloid Protein Neurotoxicity Using Antibodies Directed Against A-Beta

Project Year(s): 
2000 - 2001
Principal Investigator(s): 

Dean M. Hartley, PhD

Most Recent/Current Position(s): 

Associate Professor (Neuroscience), Rush University

Measurement of Hydrogen Peroxide Production Utilizing Intracerebral Microdialysis in Transgenic Mice Exhibiting Elevated A-Beta Peptide Levels and Amyloid Plaque Formation

Project Year(s): 
1999 - 2000
Principal Investigator(s): 

Lee E. Goldstein, MD, PhD

Most Recent/Current Position(s): 

Director, Molecular Aging and Development Laboratory & Co-Director, Boston University ADC Translational Animal Core & Associate Professor (Psychiatry, Ophthalmology, Neurology, Pathology & Laboratory Medicine, Biomedical Engineering), Boston University

Development and Characterization of a Transgenic Mouse Model for Cerebral Amyloid Angiopathy

Project Year(s): 
1999 - 2000
Principal Investigator(s): 

Steven M. Greenberg, MD, PhD

Most Recent/Current Position(s): 

Director, Hemorrhagic Stroke Research Program, Massachusetts General Hospital & Professor (Neurology), Harvard Medical School

Functional Characterization of the Alpha-2-Macroglobulin Variant Linked to Late-Onset Alzheimer's Disease

Project Year(s): 
1999 - 2000
Principal Investigator(s): 

Aleister J. Saunders, PhD

Most Recent/Current Position(s): 

Director, Drexel University RNAi Resource Center & Interim Associate Department Head & Associate Professor (Biology, Biochemistry & Molecular Biology, Neurobiology & Anatomy), Drexel University

The Role of DNA Damage in Early Stages of Alzheimer-Related Neuropathology and in Experimental Models of Cell Injury

Project Year(s): 
1999 - 2000
Principal Investigator(s): 

Emil Adamec, MD, PhD

Most Recent/Current Position(s): 

Professor (Neuroscience and Pharmacology), Lake Erie College of Osteopathic Medicine, Bradenton, FL

Beta-Amyloid Induced Neuronal Death: Mechanisms and Intervention Strategies

Project Year(s): 
1998 - 1999
Principal Investigator(s): 

Mina Yaar, MD

Most Recent/Current Position(s): 

Interim Chair & Professor (Dermatology), Boston University

The Role of the A2a Adenosine Receptor in Learning and Memory in Young and Aging Mice

Project Year(s): 
1998 - 1999
Principal Investigator(s): 

Michael A. Schwarzschild, MD, PhD

Most Recent/Current Position(s): 

Associate Professor (Neurology), Harvard Medical School

Perfusion of Entorhinal Cortex in Alzheimer's Disease

Project Year(s): 
1998 - 1999
Principal Investigator(s): 

Leena M. Hamberg, PhD, ScD

Most Recent/Current Position(s): 

Director of Clinical Trials, Massachusetts General Hospital Department of Neuroradiology

High Resolution Magic Angle Spinning Protron MR Spectroscopy

Project Year(s): 
1998 - 1999
Principal Investigator(s): 

Leo Ling Cheng, PhD

Most Recent/Current Position(s): 

Assistant Professor (Radiology & Pathology), Harvard Medical School

Syndicate content