Annual Pilot

Beta-Amyloid Deposition in Alzheimer's Disease Lens

Project Year(s): 
2003 - 2004
Principal Investigator(s): 

Lee E. Goldstein, MD, PhD

Most Recent/Current Position(s): 

Director, Molecular Aging and Development Laboratory & Co-Director, Boston University ADC Translational Animal Core & Associate Professor (Psychiatry, Ophthalmology, Neurology, Pathology & Laboratory Medicine, Biomedical Engineering), Boston University

The Insulin-Degrading Enzyme: Its Role in A-Beta and AICD Degradation In Vivo

Project Year(s): 
2003 - 2004
Principal Investigator(s): 

Suzanne Y. Guenette, PhD

Most Recent/Current Position(s): 

Assistant Professor (Neurology), Harvard Medical School

LRP-Mediated Clearance of Pre-Fibrillar Oligomeric A-Beta Species

Project Year(s): 
2003 - 2004
Principal Investigator(s): 

Robert D. Moir, PhD

Most Recent/Current Position(s): 

Assistant Professor (Neurology), Harvard Medical School

Calbindin and Cholinergic Neurons in Aging and Alzheimer's Disease

Project Year(s): 
2003 - 2004
Principal Investigator(s): 

Jing Bu, MD, PhD

Most Recent/Current Position(s): 

Investigator, Dana-Farber Cancer Institute

Structure Function Relationships in the Alzheimer's Disease Brain

Project Year(s): 
2002 - 2003
Principal Investigator(s): 

H. Diana Rosas, MD

Most Recent/Current Position(s): 

Associate Professor (Neurology), Harvard Medical School

Effects of Perioperative Hypocapnia and Hypoxia on Cellular Apoptosis

Project Year(s): 
2002 - 2003
Principal Investigator(s): 

ZhongCong Xie, MD, PhD

Most Recent/Current Position(s): 

Associate Professor (Anaesthesia), Harvard Medical School

BACE Protein and Specific Enzyme Activity in Alzheimer's Disease

Project Year(s): 
2002 - 2003
Principal Investigator(s): 

Michael C. Irizarry, MD, MPH

Most Recent/Current Position(s): 

Director, WW Epidemiology, GlaxoSmithKline, Inc.

Functional Role of Calsenilin in Alzheimer's Disease

Project Year(s): 
2002 - 2003
Principal Investigator(s): 

EunKyoung Choi, PhD

Most Recent/Current Position(s): 

Associate Professor (Neurology), Hallym University, South Korea

Molecular and Functional Characterization of Presenilin 1 Multimeric Complex

Project Year(s): 
2001 - 2002
Principal Investigator(s): 

Giuseppina Tesco, MD, PhD

Most Recent/Current Position(s): 

Assistant Professor (Neuroscience), Tufts University School of Medicine

Diffusion Tensor Imaging of White Matter Degeneration in the Alzheimer's Disease Brain

Project Year(s): 
2001 - 2002
Principal Investigator(s): 

David H. Salat, PhD

Most Recent/Current Position(s): 

Assistant Professor (Radiology), Harvard Medical School

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