Annual Pilot

BACE Protein and Specific Enzyme Activity in Alzheimer's Disease

Project Year(s): 
2002 - 2003
Principal Investigator(s): 

Michael C. Irizarry, MD, MPH

Most Recent/Current Position(s): 

Director, WW Epidemiology, GlaxoSmithKline, Inc.

Functional Role of Calsenilin in Alzheimer's Disease

Project Year(s): 
2002 - 2003
Principal Investigator(s): 

EunKyoung Choi, PhD

Most Recent/Current Position(s): 

Associate Professor (Neurology), Hallym University, South Korea

Molecular and Functional Characterization of Presenilin 1 Multimeric Complex

Project Year(s): 
2001 - 2002
Principal Investigator(s): 

Giuseppina Tesco, MD, PhD

Most Recent/Current Position(s): 

Assistant Professor (Neuroscience), Tufts University School of Medicine

Diffusion Tensor Imaging of White Matter Degeneration in the Alzheimer's Disease Brain

Project Year(s): 
2001 - 2002
Principal Investigator(s): 

David H. Salat, PhD

Most Recent/Current Position(s): 

Assistant Professor (Radiology), Harvard Medical School

Analysis of APP Processing Drosophila Genetics

Project Year(s): 
2001 - 2002
Principal Investigator(s): 

Mel B. Feany, MD, PhD

Most Recent/Current Position(s): 

Associate Professor (Pathology), Harvard Medical School

Structural Bases for Alzheimer Amyloid Fibril Formation

Project Year(s): 
2001 - 2002
Principal Investigator(s): 

Gal Bitan, PhD

Most Recent/Current Position(s): 

Assistant Professor (Neurology), University of California, Los Angeles

Website for English and Spanish-Speaking Caregivers of Elders with Alzheimer's Disease and Related Disorders

Project Year(s): 
2000 - 2001
Principal Investigator(s): 

Sue E. Levkoff, ScD

Most Recent/Current Position(s): 

Associate Professor (Psychiatry), Harvard Medical School

Investigating Metal-Mediated Redox Properties of Endogenous Human A-Beta and Oxidatively Amyloidgenic Processing APP in Alzheimer's Disease

Project Year(s): 
2000 - 2001
Principal Investigator(s): 

Xudong Huang, PhD

Most Recent/Current Position(s): 

Assistant Professor (Radiology), Harvard Medical School

The Alteration of the Beta-Amyloid Protein Neurotoxicity Using Antibodies Directed Against A-Beta

Project Year(s): 
2000 - 2001
Principal Investigator(s): 

Dean M. Hartley, PhD

Most Recent/Current Position(s): 

Associate Professor (Neuroscience), Rush University

Measurement of Hydrogen Peroxide Production Utilizing Intracerebral Microdialysis in Transgenic Mice Exhibiting Elevated A-Beta Peptide Levels and Amyloid Plaque Formation

Project Year(s): 
1999 - 2000
Principal Investigator(s): 

Lee E. Goldstein, MD, PhD

Most Recent/Current Position(s): 

Director, Molecular Aging and Development Laboratory & Co-Director, Boston University ADC Translational Animal Core & Associate Professor (Psychiatry, Ophthalmology, Neurology, Pathology & Laboratory Medicine, Biomedical Engineering), Boston University

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