5-Year Major

Regulation of Amyloid-Beta Production in Health and in Alzheimer's Disease

5-Year Major

Project Year(s):

1994 - 1998

Principal Investigator(s):

Dennis J. Selkoe, MD

Most Recent/Current Position(s):

Co-Director, Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital & Vincent and Stella Coates Professor of Neurologic Diseases, Harvard Medical School

Receptor-Coupled ADD Processing

5-Year Major

Project Year(s):

1994 - 1998

Principal Investigator(s):

John H. Growdon, MD

Most Recent/Current Position(s):

Founding Director & Clinical Core Leader, Massachusetts ADRC & Professor of Neurology, Harvard Medical School

Functional MRI in Aging and Alzheimer's Disease

5-Year Major

Project Year(s):

1994 - 1996

Principal Investigator(s):

Suzanne H. Corkin, PhD

Most Recent/Current Position(s):

Professor of Behavioral Neuroscience, Massachusetts Institute of Technology & Lecturer on Radiology, Harvard Medical School

Pathogenesis of Alzheimer's Disease

5-Year Major

Project Year(s):

1989 - 1991

Principal Investigator(s):

James E. Hamos, PhD

Most Recent/Current Position(s):

Program Director, Math and Science Partnership Program, National Science Foundation

Histochemistry of the Cystoskeleton in Alzheimer's Disease

5-Year Major

Project Year(s):

1989 - 1991

Principal Investigator(s):

Neil W. Kowall, MD

Most Recent/Current Position(s):

Director, New England Geriatric Research Education and Clinical Center & Chief of Neurology, Veterans Affairs Boston Healthcare System & Director, Boston University Alzheimer's Disease Center & Professor of Neurology and Pathology, Boston University School of Medicine

Neuronal Protease Expression

5-Year Major

Project Year(s):

1989 - 1994

Principal Investigator(s):

Ralph A. Nixon, MD, PhD

Most Recent/Current Position(s):

Director, Center of Excellence for Brain Aging and Dementia & Executive Director, Pearl Barlow Center for Memory Evaluation and Treatment & Professor of Psychiatry and Cell Biology, New York University School of Medicine

Cholinesterases in Alzheimer's Disease

5-Year Major

Project Year(s):

1989 - 1994

Principal Investigator(s):

M. Marsel Mesulam, MD

Most Recent/Current Position(s):

Director, Northwestern University Alzheimer's Disease Center & Ruth and Evelyn Dunbar Professor of Neurology and Psychiatry, Northwestern University Feinberg School of Medicine

Immunochemical Study of Proteolysis in Alzheimer's Disease

5-Year Major

Project Year(s):

1984 - 1989

Principal Investigator(s):

Ralph A. Nixon, MD, PhD

Most Recent/Current Position(s):

Cholinergic Pathology in Alzheimer's Disease

5-Year Major

Project Year(s):

1984 - 1989

Principal Investigator(s):

M. Marsel Mesulam, MD

Most Recent/Current Position(s):

Director, Northwestern University Alzheimer's Disease Center & Ruth and Evelyn Dunbar Professor of Neurology and Psychiatry, Northwestern University Feinberg School of Medicine

Neuron and Neurite Loss in Dementia: Immunocytochemical Assay by Computer Imaging

5-Year Major

Project Year(s):

1984 - 1989

Principal Investigator(s):

Joseph Rogers, PhD

Most Recent/Current Position(s):

Former President & Senior Scientist, Sun Health Research Institute & Associate Director, Arizona Alzheimer's Disease Center/Banner Alzheimer's Institute