Dementia in the News

Los Angeles Times (December 13, 2012): Alzheimer's-Plagued Columbia Region is Focus of Drug Trial

Publication Date: 
Thu, 12/13/2012

The unusually high incidence of early-onset Alzheimer's disease in this isolated cattle town has thrust it to the forefront of global efforts to find a cure for the debilitating malady.

Next spring, 100 residents of this region in northwestern Columbia who are known to carry a mutant gene linked to the disease will begin taking a therapeutic drug produced by the U.S. biotechnology firm Genentech. The five-year clinical trial, called the Alzheimer's Prevention Initiative, will cost $100 million. The effort is backed by the U.S. National Institutes of Health and includes UCLA.

National Institutes of Health (December 3, 2012): A Little Exercise Might Lengthen Life

Publication Date: 
Mon, 12/03/2012

A little physical activity can go a long way toward extending your life, regardless of your weight, a new study found. People who walked briskly or did other activity at only half the recommended amount gained nearly 2 years in life expectancy compared to inactive people. Those who exercised even more gained up to 4.5 years of life.

Boston Globe (November 23, 2012): Dr. Rudy Tanzi, Rock Star of Science

Publication Date: 
Fri, 11/23/2012

It was in 2009 when Dr. Rudy Tanzi was asked to appear in a GQ magazine photo shoot for a campaign called "Rock Stars of Science." The shoot, organized by the Geoffrey Beene Foundation, was aimed at raising awareness of scientific research by matching accomplished researchers with famous musicians. Tanzi, who heads Massachusetts General Hospital's Genetics and Aging Research Unit and teaches neurology at Harvard Medical School, was paired with a fellow Bostonian, Aerosmith guitarist Joe Perry.

New York Times (November 14, 2012): Alzheimer's Tied to Mutation Harming Immune Response

Publication Date: 
Wed, 11/14/2012

Alzheimer's researchers and drug companies have for years concentrated on one hallmark of Alzheimer’s disease: the production of toxic shards of a protein that accumulate in plaques on the brain.

New York Times (November 12, 2012): Alzheimer's Precursors Evident in Brain at Early Age

Publication Date: 
Mon, 11/12/2012

Scientists studying Alzheimer's disease are increasingly finding clues that the brain begins to deteriorate years before a person shows symptoms of dementia.

Now, research on a large extended family of 5,000 people in Columbia with a genetically driven form of Alzheimer’s has found evidence that the precursors of the disease begin even earlier than previously thought, and that this early brain deterioration occurs in more ways than has been documented before.

New York Times (October 24, 2012): The Island Where People Forget to Die

Publication Date: 
Wed, 10/24/2012

In 1943, a Greek war veteran named Stamatis Moraitis came to the United States for treatment of a combat-mangled arm. He’d survived a gunshot wound, escaped to Turkey and eventually talked his way onto the Queen Elizabeth, then serving as a troopship, to cross the Atlantic. Moraitis settled in Port Jefferson, N.Y., an enclave of countrymen from his native island, Ikaria. He quickly landed a job doing manual labor. Later, he moved to Boynton Beach, Fla. Along the way, Moraitis married a Greek-American woman, had three children and bought a three-bedroom house and a 1951 Chevrolet.

CURE Alzheimer's Fund (October 18, 2012): $5.4 Million Awarded for Research to Guide Alzheimer's Drug Development

Publication Date: 
Thu, 10/18/2012

Understanding who is most susceptible to Alzheimer's disease and developing early detection models, effective therapies and possibly a cure, is the goal of the largest single private scientific grant ever invested in Alzheimer's Whole Genome Sequencing (WGS) focused on families afficted with Alzheimer's disease.

A $5.4 million contribution announced today from the non-profit Cure Alzheimer's Fund to Massachusetts General Hospital (MGH) will allow state-of-the-art whole genome DNA sequencing to further understand the genetic roots of Alzheimer's disease.

MIT News (October 16, 2012): Brain's Language Center has Multiple Roles

Publication Date: 
Tue, 10/16/2012

A century and a half ago, French physician Pierre Paul Broca found that patients with damage to part of the brain's frontal lobe were unable to speak more than a few words. Later dubbed Broca's area, this region is believed to be critical for speech production and some aspects of language comprehension.

U.S. News & World Report (October 11, 2012): The Latest Outlook on Alzheimer's

Publication Date: 
Thu, 10/11/2012

More than 5 million Americans have Alzheimer's disease, and the nonprofit Alzheimer's Association projects that, barring major advances, 11 million to 16 million will have it by 2050 - at an annual cost of $1.1 trillion in today's dollars. In May, the government announced the first national plan to combat Alzheimer's, and one focus is the role of beta-amyloid plaques in the brain, a leading suspect in this form of dementia. U.S.

New York Times (October 10, 2012): Three Drugs to be Tested to Stave off Alzheimer's

Publication Date: 
Wed, 10/10/2012

Scientists have selected three different types of Alzheimer's drugs to be tested in the first large-scale international attempt to prevent the disease in people who are otherwise doomed to get it.

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