Dementia in the News

Harvard Gazette (April 4, 2013): Lessons from the Long-Lived

Publication Date: 
Thu, 04/04/2013

Not long ago, Karl Pillemer had a revelation.

A gerontologist with close to 30 years of experience, Pillemer, who is director of the Cornell Institute for Translational Research on Aging, realized that his research was "entirely focused on older people as problems."

National Intitutes of Health (April 2, 2013): BRAIN Initiative

Publication Date: 
Tue, 04/02/2013

The NIH Brain Resaerch through Advancing Neurotechnologies (BRAIN) Initiative is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a revolutionary new dynamic picture of the brain that, for the first time, shows how individual cells and complex neural circuits interact in both time and space.

Science Daily (March 18, 2013): Uncontrolled Hypertension Could Bring Increased Risk for Alzheimer's Disease

Publication Date: 
Mon, 03/18/2013

A study in the Journal of the American Medical Association Neurology suggests that controlling or preventing risk factors, such as hypertension, earlier in life may limit or delay the brain chnages associated with Alzheimer's disease and other age-related neurological deterioration.

New York Times (March 13, 2013): FDA Plans Looser Rules on Approving Alzheimer's Drugs

Publication Date: 
Wed, 03/13/2013

The Food and Drug Administration plans to loosen the rules for approving new treatments for Alzheimer's disease.

Drugs in clinical trial would qualify for approval if people at very early stages of the disease subtly improved their performance on memory or reasoning tests, even before they developed any obvious impairments. Companies would not have to show that the drugs improved daily, real-world functioning.

The Washington Post (March 12, 2013): Fit at 102, Ray Clark is Proof that It's Never Too Late to Start Exercising

Publication Date: 
Tue, 03/12/2013

It wasn't the toll from lugging a heavy tool box to work that finally sent Ray Clark to the gym. It was something more profound. He lost his wife of 67 years. Then he lost his daughter. He was looking for something to fill the empty hours.

"I was getting a little lazy at home, and I decided I'd go down to the exercise club," he recalled.

Harvard Gazette (March 6, 2013): Environment Counts, Alzheimer's Research Suggests

Publication Date: 
Wed, 03/06/2013

Previous studies have shown that keeping the mind active, exercising, and social interactions may help delay the onset of dementia in Alzheimer's patients.

Medscape (March 1, 2013): Eye Tests May Predict Alzheimer's Risk

Publication Date: 
Fri, 03/01/2013

Abnormalities in retinal vascular parameters (RVPs) may indicate increased amyloid plaque in the brain and can serve as biomarkers for preclinical Alzheimer's disease (AD), new research suggests.

Findings from the Australian Imaging, Biomarkers, and Lifestyle (AIBL) Flagship Study of Ageing showed that participants with AD had several significantly different RVPs, including narrower veins and a significantly higher arteriole-to-venule ratio (AVR), than their peers without AD.

AlzForum (February 22, 2013): Vascular Dementia or Alzheimer's: Is the Delineation Emerging?

Publication Date: 
Fri, 02/22/2013

When it comes to vascular brain injury, the dementia field has been mired in uncertainty. What is it, exactly? How can scientists measure and treat it? How does it realted to Alzheimer's patholology or contribute to cognitive decline? Answers to these old questions are still lacking, but two recent studies published online February 11 and 18 in JAMA Neurology suggest that vascular damage and amyloid plaques occur independently in early stages of AD.

AlzForum (February 1, 2013): HAI - Standardizing Amyloid PET: The Centiloid Project

Publication Date: 
Fri, 02/01/2013

In your mind, does the word "centiloid" conjure up images of a small creature with too many legs? Instead, think centimeter yardstick, or thermometer. A centiloid is a proposed unit of measure on a unified scale for all amyloid-beta imaging tracers used in positron emission tomography (PET). Alzheimer's disease scientists use a handful of ligands in research already, and while the FDA thus far has approved only one - Amyvid - for clinical use, other approvals appear likely. Since each tracer has its own chracteristic signal strength, comparing them remains difficult.

Science Daily (January 28, 2013): Guidelines for Brain Amyloid Imaging in Alzheimer's

Publication Date: 
Mon, 01/28/2013

Only recently has it become possible to create high-quality images of the brain plaques characteristic of Alzheimer's disease in living people through positron emission tomography (PET). Even so, questions remain about what can be learned from these PET images and which people should have this test.

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