A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer's disease (AD). The research, published by Cell Press in the November 12 issue of the journal Neuron, finds that the novel gene interacts with a key cellular enzyme previously-linked with AD pathology, thereby uncovering a new strategy for treating this devastating disorder.
As cases of Alzheimer's disease continue to soar in the United States, with as many as 16 million Americans expected to be diagnosed by 2015, according to the Alzheimer's Association, more and more youths are faced with the grim reality that one day, grandma or grandpa may forget who they are.
Joe LoGuidice and Bryant Soohoo are all too aware of that possibility -- the Fairfield County teens both have grandparents diagnosed with Alzheimer's, or a related from of dementia.
Older people with stronger muscles are at reduced risk of developing Alzheimer's disease compared to their weaker peers, a new study shows.
Dr. Patricia A. Boyle of Rush Alzheimer's Disease Center in Chicago and her colleagues found that the greater a person's muscle strength, the lower their likelihood of being diagnosed with Alzheimer's over a four-year period.
Middle-aged women with high levels of a specific amino acid in their blood are twice as likely to suffer from Alzheimer's many years later, reveals a thesis from the Sahlgrenska Academy at the University of Gothenburg, Sweden. This discovery could lead to a new and simple way of determining who is at risk long before there are any signs of the illness.
With the flu continuing to spread nationwide, imagine adding the virus into the mix when someone is already coping with a chronic illness like Alzheimer's disease. In an effort to help families manage this situation, the Alzheimer's Foundation of America (AFA) today released tips for caregivers of individuals with dementia who believe that they or the people they are caring for have the flu.
When Charles Tang's wife Amy 76, was diagnosed with Alzheimer's several years ago, he started looking for a support group for himself. He was shocked to find none were available in his native Chinese language.
"Every time I was attending the education meetings at the Alzheimer's Association NYC chapter, I found that I was the only one who was Chinese or even Asian," said Tang, 84, of Manhattan.
High blood pressume, evidence of arterial disease and markers of inflammation in the blood in middle age appear more common in inidividuals whose parents have Alzheimer's disease than in individuals without a parental history of the condition, according to a report in the November issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
A group of drugs used to treat epilepsy may also treat Alzheimer's and Parkinson's disease.
New research shows treatment with T-type calcium channel blockers, used to treat epilepsy, protected nerve cells from the brains of mice that can be damaged by neurodegenerative disorders such as Alzheimer's and Parkinson's disease.
The surgeon who removed the five-year-old boy's tonsils in 1959 had never seen anything like them. Instead of pinkish lobes, the boy's tonsils were huge and orange. Thinking that their extraordinary appearance might signal a rare malignancy, the surgeon sent the tonsils to the Armed Forces Pathology Institute in Washington, DC. Though researchers there found no cancer, they did discover the reason for the tissue's abnomal size and color: Its cells were bloated with cholesterol.
There is no scientific proof that patients with moderate or severe Alzheimer's disease benefit from drugs containing the agent Memantine. This is the conclusion in the final report that the Institute for Quality and Efficiency in Health Care (IQWiG) published in September 2009.
The report is part of a broader commission awarded by the Federal Joint Committee (G-BA) to assess both drug and non-drug therapy options for Alzheimer's disease. In addition to Memantine, IQWiG has investigated cholinesterase inhibitors, Ginkgo Biloba and non-drug therapy alternatives.