Of the millions of animals on Earth, including the relative handful that are considered the most intelligent - including apes, whales, crows, and owls - only humans experience the severe age-related decline in mental abilities marked by Alzheimer's disease.
To Bruce Yankner, professor of pathology and neurology at Harvard Medical School (HMS), it's pretty clear that evolution is to blame.
The use of repetitive anesthesia with isoflurace (one of the most common anesthetics by inhalation) increases the risk of developing changes similar to those observed in AD brains in mice with mutations of the amyloid precursor protein (APP).
In 1950, when Marybeth Solinski was born, a diagnosis of Down syndrome was practically a death sentence.
Children with the condition often died before their 10th birthday.
Yet Solinski, at 59, has outlived her parents. She has even joined AARP.
Her longevity illustrates the dramatic progress for people with Down syndrome. Thanks to better medical care, the average life expectancy for a child with Down syndrome is now 60 years, according to the National Down Syndrome Society, which estimates that about 400,000 people are living with the condition in the USA.
18F-FDG PET identified the average increase amyloid-beta plaques among individuals whose mothers had been diagnosed with Alzheimer's disease compared to others with no family history of dementia, according to research findings published online March 15 in the Proceedings of the National Academy of Sciences.
A team of scientists from Cambridge and Sweden have discovered a molecule that can prevent a toxic protein involved in Alzheimer's disease from building up in the brain. Dr. Leila Luheshi, of the Department of Genetics at University of Cambridge, et al. found that in test tube studies, the molecule not only prevents the protein from forming clumps but can also reverse the potentially toxic process. Then, using fruit flies engineered to develop a fly equivalent of Alzheimer's disease, they showed that the same molecule effectively "cures" the insects of the disease.
Busloads of students from Washington, D.C., area schools will visit the National Museum of Health and Medicine at Walter Reed Army Medical Center on March 17 and 18 for a special experience. These students, grades five through eight, will participated in the museum's 11th annual Brain Awarenesss Week. During these two days, scientists from five Institutes at the National Institutes of Health will host interactive sessions focusing on brain health and neuroscience.
In our house, we talk a lot about long-term care. My dad is 92 and afflicted by dementia and failing eyesight.
Luckily, I'm blessed with three wonderful siblings who do the hard work of caring for my father and making sure he can stay in his own home in suburban Detriot. But my visits from Brooklyn to spell my siblings are becoming increasingly complex, as my father needs more care and loses track of exactly who I am.
It had been three years since her 86-year-old mother, Eleanor Schwartz, moved in with her and her husband in their home in Johnsburg, Ill. Mrs. Schwartz has Alzheimer's disease and has trouble moving around, so Mrs. Egebrecht helps her mother with her shower each day, makes sure she's fed and takes her on small excursions to the mall in a portable wheelchair. The routine includes occasionally reminding her mother of what day it is and where she's living.