Dementia in the News

Broad Institute (March 13, 2015): For Drivers of Alzheimer’s Disease, Check the Roadmap

Publication Date: 
Fri, 03/13/2015

Recently, the BroadMinded blog highlighted the exciting science emerging from the Roadmap Epigenomics program, resulting in the most comprehensive map of the human epigenome — the collection of chemical changes to DNA and its supporting proteins that help control how genes are turned on or off.

News Medical (March 11, 2015): Two Researchers to Receive Potamkin Prize for Research on Alzheimer's Disease

Publication Date: 
Wed, 03/11/2015

The American Academy of Neurology and the American Brain Foundation are awarding the 2015 Potamkin Prize for Research in Pick's, Alzheimer's and Related Diseases to Peter Davies, PhD, of the Feinstein Institute for Medical Research in Manhasset, NY, and Reisa A. Sperling, MD, of the Brigham and Women's Hospital and Massachusetts General Hospital in Boston.

Boston Globe (March 6, 2015): Older and Wiser? Some Brain Functions Improve as We Age

Publication Date: 
Fri, 03/06/2015

There is hope for aging baby boomers.

The ability to recall names and faces with lightning speed may start to fade in one’s 20s, but our capability to perform other functions, such as learning new words, doesn’t peak until decades later, according to a new study by Boston scientists.

National Institute on Aging (NIA): NIH-Led Effort Launches Big Data Portal for Alzheimer’s Drug Discovery

Publication Date: 
Thu, 03/05/2015

A National Institutes of Health-led public-private partnership to transform and accelerate drug development achieved a significant milestone today with the launch of a new Alzheimer’s Big Data portal - including delivery of the first wave of data - for use by the research community. The new data sharing and analysis resource is part of the Accelerating Medicines Partnership (AMP), an unprecedented venture bringing together NIH, the U.S.

Reuters (March 3, 2015): Harvard Prevention Trial Studies Tau, Alzheimer's Other Protein

Publication Date: 
Mon, 03/02/2015

Alzheimer's researchers at Harvard for the first time are scanning the brains of healthy patients for the presence of a hallmark protein called tau, which forms toxic tangles of nerve fibers associated with the fatal disease.

The new scans are part of a large clinical trial called Anti-Amyloid Treatment in Asymptomatic Alzheimer's or A4, the first designed to identify and treat patients in the earliest stages of Alzheimer's, before memory loss begins.

Massachusetts General Hospital (February 27, 2015): Venture Capital Fuels Alzheimer’s Breakthroughs

Publication Date: 
Fri, 02/27/2015

Venture capitalists are known for making bold bets on high-risk projects that have the potential for huge payoffs. Today, driven by that vision, a group of business leaders who founded the Cure Alzheimer’s Fund (CAF) to find a cure for this disease are seeing important returns on their investment in research at Mass General and beyond.

The scientific results the CAF support has brought about are nothing short of game changing as Mass General researchers resolve some long-unanswered questions about how Alzheimer’s disease develops.

Harvard Gazette (January 25, 2015): A New Understanding of Alzheimer's

Publication Date: 
Wed, 02/25/2015

Although natural selection is often thought of as a force that determines the adaptation of replicating organisms to their environment, Harvard researchers have found that selection also occurs at the level of neurons, which are post-mitotic cells, and plays a critical role in the emergence of Alzheimer’s disease.

AlzForum (February 23, 2015): More Needed Than Ever, Brain Banks are Modernizing But Face Funding Crunch

Publication Date: 
Mon, 02/23/2015

Banked brain tissue enables crucial advances in the understanding and treatment of degenerative disorders. As appreciation of the many different variants of neurodegenerative disease is growing, well-preserved tissue is in more demand than ever. Are the brain banks up to the task? Modern banks are harmonizing protocols, combining their inventories in online listings, and maintaining databases of detailed longitudinal data. At the same time, these institutions face funding shortfalls that threaten continued progress.

MIT News (February 18, 2015): Epigenomics of Alzheimer’s Disease Progression

Publication Date: 
Wed, 02/18/2015

Our susceptibility to disease depends both on the genes that we inherit from our parents and on our lifetime experiences. These two components - nature and nurture - seem to affect very different processes in the context of Alzheimer's disease, according to a new study published today in the journal Nature.

New York Times (February 12, 2015): Studying Oversize Brain Cells for Links to Exceptional Memory

Publication Date: 
Thu, 02/12/2015

In 2010, a graduate student named Tamar Gefen got to know a remarkable group of older people.

They had volunteered for a study of memory at the Feinberg School of Medicine at Northwestern University. Although they were all over age 80, Ms. Gefen and her colleagues found that they scored as well on memory tests as people in their 50s. Some complained that they remembered too much.

She and her colleagues referred to them as SuperAgers. Many were also friends. “A couple tried to set me up with their grandsons,” Ms. Gefen said.

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