Biblio

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2016
C. M. Karch, Ezerskiy, L. A., Bertelsen, S., and Goate, A. M., Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci., PLoS One, vol. 11, no. 2, p. e0148717, 2016.
M. T. W. Ebbert, Boehme, K. L., Wadsworth, M. E., Staley, L. A., Mukherjee, S., Crane, P. K., Ridge, P. G., and Kauwe, J. S. K., Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk., Alzheimers Dement, vol. 12, no. 2, pp. 121-9, 2016.
T. J. Montine, Monsell, S. E., Beach, T. G., Bigio, E. H., Bu, Y., Cairns, N. J., Frosch, M., Henriksen, J., Kofler, J., Kukull, W. A., Lee, E. B., Nelson, P. T., Schantz, A. M., Schneider, J. A., Sonnen, J. A., Trojanowski, J. Q., Vinters, H. V., Zhou, X. - H., and Hyman, B. T., Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease., Alzheimers Dement, vol. 12, no. 2, pp. 164-9, 2016.
J. M. Ringman, Monsell, S., Ng, D. W., Zhou, Y., Nguyen, A., Coppola, G., Van Berlo, V., Mendez, M. F., Tung, S., Weintraub, S., Mesulam, M. - M., Bigio, E. H., Gitelman, D. R., Fisher-Hubbard, A. O., Albin, R. L., and Vinters, H. V., Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database., J Neuropathol Exp Neurol, vol. 75, no. 3, pp. 284-90, 2016.
G. Jun, Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. - C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. - S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A., Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. - H., Boland, A., Becker, T., Kukull, W. A., van der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. - F., Hampel, H., Kamboh, M. I., de Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., van Duijn, C. M., Schellenberg, G. D., and Farrer, L. A., A novel Alzheimer disease locus located near the gene encoding tau protein., Mol Psychiatry, vol. 21, no. 1, pp. 108-17, 2016.
A. Serrano-Pozo, Betensky, R. A., Frosch, M. P., and Hyman, B. T., Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease., Am J Pathol, vol. 186, no. 2, pp. 375-84, 2016.
A. Viswanathan, Greenberg, S. M., and Scheltens, P., Role of Vascular Disease in Alzheimer-Like Progressive Cognitive Impairment., Stroke, vol. 47, no. 2, pp. 577-80, 2016.
2015
Y. Hye Kim, Choi, S. Hoon, D'Avanzo, C., Hebisch, M., Sliwinski, C., Bylykbashi, E., Washicosky, K. J., Klee, J. B., Brüstle, O., Tanzi, R. E., and Kim, D. Yeon, A 3D human neural cell culture system for modeling Alzheimer's disease., Nat Protoc, vol. 10, no. 7, pp. 985-1006, 2015.
S. Park, Lee, S., Lee, Y., Herold, C., Hooli, B., Mullin, K., Park, T., Park, C., Bertram, L., Lange, C., Tanzi, R., and Won, S., Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families., BMC Med Genet, vol. 16, p. 62, 2015.
J. B. Toledo, Zetterberg, H., van Harten, A. C., Glodzik, L., Martinez-Lage, P., Bocchio-Chiavetto, L., Rami, L., Hansson, O., Sperling, R., Engelborghs, S., Osorio, R. S., Vanderstichele, H., Vandijck, M., Hampel, H., Teipl, S., Moghekar, A., Albert, M., Hu, W. T., Argilés, J. A. Monge, Gorostidi, A., Teunissen, C. E., De Deyn, P. P., Hyman, B. T., Molinuevo, J. L., Frisoni, G. B., Linazasoro, G., de Leon, M. J., van der Flier, W. M., Scheltens, P., Blennow, K., Shaw, L. M., and Trojanowski, J. Q., Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects., Brain, vol. 138, no. Pt 9, pp. 2701-15, 2015.
J. Barnes, Dickerson, B. C., Frost, C., Jiskoot, L. C., Wolk, D., and van der Flier, W. M., Alzheimer's disease first symptoms are age dependent: Evidence from the NACC dataset., Alzheimers Dement, vol. 11, no. 11, pp. 1349-57, 2015.
C. D'Avanzo, Aronson, J., Kim, Y. Hye, Choi, S. Hoon, Tanzi, R. E., and Kim, D. Yeon, Alzheimer's in 3D culture: challenges and perspectives., Bioessays, vol. 37, no. 10, pp. 1139-48, 2015.
A. M. Pooler, Polydoro, M., Maury, E. A., Nicholls, S. B., Reddy, S. M., Wegmann, S., William, C., Saqran, L., Cagsal-Getkin, O., Pitstick, R., Beier, D. R., Carlson, G. A., Spires-Jones, T. L., and Hyman, B. T., Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease., Acta Neuropathol Commun, vol. 3, p. 14, 2015.
E. Liu, Schmidt, M. E., Margolin, R., Sperling, R., Koeppe, R., Mason, N. S., Klunk, W. E., Mathis, C. A., Salloway, S., Fox, N. C., Hill, D. L., Les, A. S., Collins, P., Gregg, K. M., Di, J., Lu, Y., I Tudor, C., Wyman, B. T., Booth, K., Broome, S., Yuen, E., Grundman, M., and H Brashear, R., Amyloid-β 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials., Neurology, vol. 85, no. 8, pp. 692-700, 2015.
B. J. Guercio, Donovan, N. J., Munro, C. E., Aghjayan, S. L., Wigman, S. E., Locascio, J. J., Amariglio, R. E., Rentz, D. M., Johnson, K. A., Sperling, R. A., and Marshall, G. A., The Apathy Evaluation Scale: A Comparison of Subject, Informant, and Clinician Report in Cognitively Normal Elderly and Mild Cognitive Impairment., J Alzheimers Dis, vol. 47, no. 2, pp. 421-32, 2015.
A. Serrano-Pozo, Qian, J., Monsell, S. E., Betensky, R. A., and Hyman, B. T., APOEε2 is associated with milder clinical and pathological Alzheimer disease., Ann Neurol, vol. 77, no. 6, pp. 917-29, 2015.
J. M. Mc Donald, O'Malley, T. T., Liu, W., Mably, A. J., Brinkmalm, G., Portelius, E., Wittbold, W. M., Frosch, M. P., and Walsh, D. M., The aqueous phase of Alzheimer's disease brain contains assemblies built from ∼4 and ∼7 kDa Aβ species., Alzheimers Dement, vol. 11, no. 11, pp. 1286-305, 2015.
M. Ghani, Reitz, C., Cheng, R., Vardarajan, B. Narayan, Jun, G., Sato, C., Naj, A., Rajbhandary, R., San Wang, L. -, Valladares, O., Lin, C. - F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N., Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., M Fallin, D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., M Kamboh, I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St George-Hyslop, P., Mayeux, R., and Rogaeva, E., Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals., JAMA Neurol, vol. 72, no. 11, pp. 1313-23, 2015.
A. S. Fleisher, Chen, K., Quiroz, Y. T., Jakimovich, L. J., Gomez, M. Gutierrez, Langois, C. M., Langbaum, J. B. S., Roontiva, A., Thiyyagura, P., Lee, W., Ayutyanont, N., Lopez, L., Moreno, S., Muñoz, C., Tirado, V., Acosta-Baena, N., Fagan, A. M., Giraldo, M., Garcia, G., Huentelman, M. J., Tariot, P. N., Lopera, F., and Reiman, E. M., Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study., JAMA Neurol, vol. 72, no. 3, pp. 316-24, 2015.
S. D. Østergaard, Mukherjee, S., Sharp, S. J., Proitsi, P., Lotta, L. A., Day, F., Perry, J. R. B., Boehme, K. L., Walter, S., Kauwe, J. S., Gibbons, L. E., Larson, E. B., Powell, J. F., Langenberg, C., Crane, P. K., Wareham, N. J., and Scott, R. A., Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study., PLoS Med, vol. 12, no. 6, p. e1001841; discussion e1001841, 2015.
M. W. Albers, Gilmore, G. C., Kaye, J., Murphy, C., Wingfield, A., Bennett, D. A., Boxer, A. L., Buchman, A. S., Cruickshanks, K. J., Devanand, D. P., Duffy, C. J., Gall, C. M., Gates, G. A., Granholm, A. - C., Hensch, T., Holtzer, R., Hyman, B. T., Lin, F. R., McKee, A. C., Morris, J. C., Petersen, R. C., Silbert, L. C., Struble, R. G., Trojanowski, J. Q., Verghese, J., Wilson, D. A., Xu, S., and Zhang, L. I., At the interface of sensory and motor dysfunctions and Alzheimer's disease., Alzheimers Dement, vol. 11, no. 1, pp. 70-98, 2015.
L. G. Apostolova, Hwang, K. S., Avila, D., Elashoff, D., Kohannim, O., Teng, E., Sokolow, S., Jack, C. R., Jagust, W. J., Shaw, L., Trojanowski, J. Q., Weiner, M. W., and Thompson, P. M., Brain amyloidosis ascertainment from cognitive, imaging, and peripheral blood protein measures., Neurology, vol. 84, no. 7, pp. 729-37, 2015.
Y. T. Quiroz, Schultz, A. P., Chen, K., Protas, H. D., Brickhouse, M., Fleisher, A. S., Langbaum, J. B., Thiyyagura, P., Fagan, A. M., Shah, A. R., Muniz, M., Arboleda-Velasquez, J. F., Muñoz, C., Garcia, G., Acosta-Baena, N., Giraldo, M., Tirado, V., Ramírez, D. L., Tariot, P. N., Dickerson, B. C., Sperling, R. A., Lopera, F., and Reiman, E. M., Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study., JAMA Neurol, vol. 72, no. 8, pp. 912-9, 2015.
D. Perry, Sperling, R., Katz, R., Berry, D., Dilts, D., Hanna, D., Salloway, S., Trojanowski, J. Q., Bountra, C., Krams, M., Luthman, J., Potkin, S., Gribkoff, V., Temple, R., Wang, Y., Carrillo, M. C., Stephenson, D., Snyder, H., Liu, E., Ware, T., McKew, J., F Fields, O., Bain, L. J., and Bens, C., Building a roadmap for developing combination therapies for Alzheimer's disease., Expert Rev Neurother, vol. 15, no. 3, pp. 327-33, 2015.
G. Chan, White, C. C., Winn, P. A., Cimpean, M., Replogle, J. M., Glick, L. R., Cuerdon, N. E., Ryan, K. J., Johnson, K. A., Schneider, J. A., Bennett, D. A., Chibnik, L. B., Sperling, R. A., Bradshaw, E. M., and De Jager, P. L., CD33 modulates TREM2: convergence of Alzheimer loci., Nat Neurosci, vol. 18, no. 11, pp. 1556-8, 2015.

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