Annual Pilot

FE65 Proteins Modulate APP Processing and Function

Project Year(s): 2004 - 2005

Principal Investigator(s):

Yang Chang, MD, PhD

Most Recent/Current Position(s):

Investigator, Wyeth Pharamaceuticals, Inc.

Calbindin and Cholinergic Neurons in Aging and Alzheimer's Disease

Project Year(s): 2003 - 2004

Principal Investigator(s):

Jing Bu, MD, PhD

Most Recent/Current Position(s):

Investigator, Dana-Farber Cancer Institute

LRP-Mediated Clearance of Pre-Fibrillar Oligomeric A-Beta Species

Project Year(s): 2003 - 2004

Principal Investigator(s):

Robert D. Moir, PhD

Most Recent/Current Position(s):

Assistant Professor (Neurology), Harvard Medical School

The Insulin-Degrading Enzyme: Its Role in A-Beta and AICD Degradation In Vivo

Project Year(s): 2003 - 2004

Principal Investigator(s):

Suzanne Y. Guenette, PhD

Most Recent/Current Position(s):

Assistant Professor (Neurology), Harvard Medical School

Beta-Amyloid Deposition in Alzheimer's Disease Lens

Project Year(s): 2003 - 2004

Principal Investigator(s):

Lee E. Goldstein, MD, PhD

Most Recent/Current Position(s):

Director, Molecular Aging and Development Laboratory & Co-Director, Boston University ADC Translational Animal Core & Associate Professor (Psychiatry, Ophthalmology, Neurology, Pathology & Laboratory Medicine, Biomedical Engineering), Boston University

Functional Role of Calsenilin in Alzheimer's Disease

Project Year(s): 2002 - 2003

Principal Investigator(s):

EunKyoung Choi, PhD

Most Recent/Current Position(s):

Associate Professor (Neurology), Hallym University, South Korea

BACE Protein and Specific Enzyme Activity in Alzheimer's Disease

Project Year(s): 2002 - 2003

Principal Investigator(s):

Michael C. Irizarry, MD, MPH

Most Recent/Current Position(s):

Director, WW Epidemiology, GlaxoSmithKline, Inc.

Effects of Perioperative Hypocapnia and Hypoxia on Cellular Apoptosis

Project Year(s): 2002 - 2003

Principal Investigator(s):

ZhongCong Xie, MD, PhD

Most Recent/Current Position(s):

Associate Professor (Anaesthesia), Harvard Medical School

Structure Function Relationships in the Alzheimer's Disease Brain

Project Year(s): 2002 - 2003

Principal Investigator(s):

H. Diana Rosas, MD

Most Recent/Current Position(s):

Associate Professor (Neurology), Harvard Medical School

Structural Bases for Alzheimer Amyloid Fibril Formation

Project Year(s): 2001 - 2002

Principal Investigator(s):

Gal Bitan, PhD

Most Recent/Current Position(s):

Assistant Professor (Neurology), University of California, Los Angeles

Annual Pilot

NIH/NIA P50 Federal Grant