Annual Pilot

Are Some Human Brains Able To Tolerate The Insult of A-Beta?

Project Year(s): 2010 - 2011

Principal Investigator(s):

M. Teresa Gomez-Isla, MD, PhD

Most Recent/Current Position(s):

Associate Professor (Neurology), Harvard Medical School

Microglia-Migration Modulation by Amyloid Beta during the Progression of Alzheimer's Disease

Project Year(s): 2010 - 2011

Principal Investigator(s):

Daniel Irimia, MD, PhD

Most Recent/Current Position(s):

Assistant Professor (Surgery), Harvard Medical School

Application of Ultrahigh Resolution MRI to Develop Imaging Biomarkers in Frontotemporal Lobar Degeneration

Project Year(s): 2009 - 2010

Principal Investigator(s):

Scott M. McGinnis, MD

Most Recent/Current Position(s):

Instructor (Neurology), Harvard Medical School

Effect of Cerebral Hypoperfusion on Beta-Amyloid Deposition

Project Year(s): 2009 - 2010

Principal Investigator(s):

Steven M. Greenberg, MD, PhD

Most Recent/Current Position(s):

Professor (Neurology), Harvard Medical School

Subclinical Paroxysmal EEG Abnormalities in Alzheimer's Disease

Project Year(s): 2009 - 2010

Principal Investigator(s):

Sydney S. Cash, MD, PhD

Most Recent/Current Position(s):

Associate Professor (Neurology), Harvard Medical School

Neuroanatomical Changes in Alzheimer's Disease

Project Year(s): 2008 - 2009

Principal Investigator(s):

Tara L. Spires-Jones, DPhil

Most Recent/Current Position(s):

Assistant Professor (Neurology), Harvard Medical School

Anosmia as a Sentinel for Alzheimer's Disease: Precision of Axon Targeting in the Olfactory Bulbs of Alzheimer's Disease Patients

Project Year(s): 2008 - 2009

Principal Investigator(s):

Mark W. Albers, MD, PhD

Most Recent/Current Position(s):

Assistant Professor (Neurology), Harvard Medical School

Cortical Morphological Consequences of Subcortical Vascular Pathology in Cerebral Amyloid Angiopathy

Project Year(s): 2008 - 2009

Principal Investigator(s):

Anand Viswanathan, MD, PhD

Most Recent/Current Position(s):

Associate Director, Massachusetts General Hospital Telestroke Services & Assistant Professor of Neurology, Harvard Medical School

Investigating Accumulation of the Mitochondrial Atpase Subunit C Protein as a Marker for Autophagy Dysfunction in Neurodegenerative Disease

Project Year(s): 2008 - 2009

Principal Investigator(s):

Susan L. Cotman, PhD

Most Recent/Current Position(s):

Assistant Professor (Neurology), Harvard Medical School

Integrating Neuroimage Data with Existing Biomedical Data in the MassADRC's Web-Based Database Query System

Project Year(s): 2007 - 2008

Principal Investigator(s):

Timohty W. Clark, MS & Randy L. Buckner, PhD

Most Recent/Current Position(s):

Timothy W. Clark, MS: Director, Center for Interdisciplinary Informatics, Mass General Institute for Neurodegenerative Disease & Instructor (Neurology), Harvard Medical School

Randy L. Buckner, PhD: Director, Psychiatric Neuroimaging Research Program, Harvard/MIT Athinoula A. Martinos Center for Biomedical Imaging & Professor (Psychology and Neuroscience), Harvard University & Lecturer (Radiology), Harvard Medical School

Annual Pilot

NIH/NIA P50 Federal Grant